Research Grant

List of research grants in the Department of Biomedical Sciences

No.

Title

Name

Role

Year

Source

Amount (RM)

1.

Antimicrobial Properties If Local Plant Extract Investigated by Different Approaches of Chemical Extraction and Antimicrobial Assay

Mohd Nasir Mohd Desa

Principal Investigator

2012

RUGS

15,000

2.

Invitro Effect of Phaleria Macrocarpa Aqueous on Glucose Uptake and Metabolism of Hepatocytes (HEP G2 Cells) and Adipocytes (3T3 L1)

Mohamad Aziz Dollah

Principal Investigator

2012

RUGS

15,000

3.

Elucidation of ImmuneResponses to Candida Tropicalis Infection in Immunesuppressed and Immunicompetent Mice Model

Chong Pei Pei

Principal Investigator

2012

RUGS

15,000

4.

Pathogenesis and Host Response Against Medically Important Candida species in an Acute Systemic Candidiasis Mice Model

Chong Pei Pei

Principal Investigator

2012

RUGS

125,000

5.

Chromoson Aberration in Malaysian Population Following Radiation Exposure using Cytokinesis Blocked Micronuclei assay technique

Mohamad Aziz Dollah

Principal Investigator

2012

RUGS

15,000

6.

Comparative gene expression analysis of virulence determinants in human isolates of Streptococcus pneumoniae with different antibiotic susceptibility profiles in a cell cultures-infection model

Mohd Nasir Mohd Desa

Principal Investigator

2012

RUGS

130,000

7.

Effects of interferon gamma on endothelial hyperpermeability in vitro

Zuraini Ahmad

Principal Investigator

2012

RUGS

10,000

8.

Hepatoprotective and Antiulcer Activities of Methanol Extact of Dicranopteris linearis Leaf : Determination of Their Mechanisms of Actions and Isolation of the Responsible bioactive Compounds

Zainul Amiruddin Zakaria

Principal Investigator

2012

RUGS

10,000

9.

Haruan Traditional Extract (THE) as Therapeutic Agent

Abdul Manan Mat Jais

Principal Investigator

2012

RUGS

200,000

10.

Enhancement of genetically engineers salmonella enterica serovar Agona knockout strain as a potential antitumor agent

Cheah Yoke Kqueen

Principal Investigator

2012

RUGS

318,500

11.

In vivo investigationof the analgesic and anti- arthritic effect of zerumbone on completeFreund's adjuvant (CFA)-induced rheumatiodal arthritis model in rats

Mohd Roslan Sulaiman

Principal Investigator

2012

SCIENCEFUND

284,400

12.

Understanding the inhibitory effects of intermediates of Dysidamide, a spiroisoxazoline, against proinflammatory mediators synthesis in the in vitro (murine monocytic macrophage RAW 264.7 cells) and confirmation of their effectiveness using in vivo animal

Zainul Amiruddin Zakaria

Principal Investigator

2012

FRGS

100,600

13.

In vivo evaluation of antipruritic activities of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxy-3-methoxybenzylidene) cyclohexanone, (BHMC) in mice

Ahmad Akira Omar Farouk

Principal Investigator

2012

FRGS

81,100

14.

The inducibility of tocopherol transfer protein (-TTP) expression to reduce biodiscrimination of other E vitamers absorption

Huzwah Khaza'ai

Principal Investigator

2012

FRGS

60,850

15.

Ficus deltoidea: anti-nociceptive and anti-inflammatory activities, the mechanisms of actions

Mohd Khairi Hussain

Principal Investigator

2012

FRGS

136,600

16.

In Vitro Revearsal Effect of Zerumbone on Allergen-Induced Airway Epithelial Disruption in Asthma

Tham Chau Ling

Principal Investigator

2012

Antarabangsa

(MSTF)

20,000

17.

Isolation, Bioprospecting and Phylogenetic Analysis of Rare Actinobacteria from Greenwich Island Antartica

Cheah Yoke Kqueen

Principal Investigator

2013

GP-IPS

15,000

18.

Identification and Bioactive Potential of Endophytes Isolated from Clinicanthus Nutans in Malaysia

Cheah Yoke Kqueen

Principal Investigator

2013

GP-IPS

15,000

19.

The Influence of β-defensins Copy Number Variable Gene in Relation to Inflammation in Diabetic Patients

Suhaili Abu Bakar @ Jamaludin

Principal Investigator

2013

GP-IPS

15,000

20.

Investigation of the analgesic property of a chalcone, cardamonin (2', 4',-dihydroxy-6'-methoxychalcone ) in animal models-induces nociception

Mohd Roslan Sulaiman

Principal Investigator

2013

GP-Individu Berprestasi Tinggi

151,000

21.

Genomic analysis on the evolution of beta defensin gene and copy number in human and selected non-human primates in Malaysia

Suhaili Abu Bakar @ Jamaludin

Principal Investigator

2013

GP-IPS

15,000

22.

Potential Angiopreventive Agent of Benzoquinonoid Compound from Ardisia Crispa Root In Vitro and In Vivo.

 Roslida Abd Hamid

Principal Investigator

2013

ERGS

130,000

23.

Inhibitory Effect of 2,4,6,-trihydroxy-3-geranylacetophenone (tHGA) on Mast Cell Degranulation in Allergic Asthma

Tham Chau Ling

Principal Investigator

2013

ERGS

172,000

24.

Comparative Genetic and Phenotypic Analyses of Colonizing and Invasive Group B Stretococcus (GBS) and the Genomic Approach

Mohd Nasir Mohd Desa

Principal Investigator

2013

ERGS

111,000

25.

Deterrmination of molecular targets and anti anti-inflammatory effects of tHGA in endotoxin-induced vascular endothelial dysfunction and lethal sepsis in mice

Tham Chau Ling

Principal Investigator

2013

FRGS

144,000

26.

Mechanistic studies of (2E)-2-[2-(cyclohexylcarbamothioy) hydrazinylidene]propanoic acid induced anti-inflammation: Possible use in Rheumatic arthritis.

Muhammad Nazrul Hakim Abdullah

Principal Investigator

2013

FRGS

150,000

27.

Investigation of The Antiallodynic and Antihyperalgesic Properties of Zerumbone In an Animal Model of Neuropathic Pain

Enoch Kumar A/L Perimal

Principal Investigator

2013

FRGS

134,500

28.

Governance Of The Human Nuclear Importin Protein KPNA2 by Xenobiotics

Manraj Singh Cheema

Principal Investigator

2013

FRGS

130,000

29.

Relationship of copy number variables genes: CCL3L1 and beta defensins, and viral load, in influencing HIV/AIDs susceptibility, progression and severity.

Suhaili Binti Abu Bakar @ Jamaludin

Principal Investigator

2013

FRGS

148,000

30.

Targetting integrated Hepatitis B Viral VNA Sequences bt YQ-NLC for treatment of liver cancer

Sharifah Sakinah bt Syed Alwi

Principal Investigator

2014

GP-IPM

50,000

31.

Investigation of the Antialloynic and Anthyperalgesic Properties of Cardamonin in an Animal Model of Neuopathic Pain

Enoch Kumar Perimal

Principal Investigator

2014

GP-IPM

49,000

32.

Possible endothelial barrier protection effect by Stachytarpheta Jamicensis (L.) Vahl

Yong Yoke Keong

Principal Investigator

2014

GP-IPM

50,000

33.

Determination of Protective Effect of THGA on Endotoxin- Induced Lethal Sepsis in Mice

Tham Chau Ling

Principal Investigator

2014

GP-IPS

15,000

34

Preliminary Investigatons On The Development of Antitumor-Promoting Reated Phytopharmaceutical Products From Dicranopteris Linearis

Siti Farah Tohid

Principal Investigator

2014

GP-IPM

33,000

35.

Determination of mechanistic pathways underlying the antitumor-promoting and anticancer activities of Dicranopteris linearis: Towards the identification of D.linearis-based bioactive compounds.

Siti Farah Binti Md Tohid

Principal Investigator

2014

FRGS

95,000

36.

Determination of molecular targets and anti-invasive effects of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone or BHMC in hypoxia-induced human cancer cells

Nur Fariesha Binti Md Hashim

Principal Investigator

2014

FRGS

155,880

37.

Exploration of multi functional role of miRNA interaction with organometallic compounds, cells and phenomics in relation with cancer.

Cheah Yoke Kqueen

Principal Investigator

2014

TRGS

688,000

38.

Elucidation of mechanism of anti-arthritic action of benzoquinoneisolated from Ardisia crispa root,in vivo

Roslida Binti Abd Hamid @ Abdul Razak

Principal Investigator

2014

FRGS

106,000

39.

Targeting the mechanistic effect of Thymoquinone-nanostructured lipid carrier (TQ-NLC) in cell migration and regeneration in normal and diabetic condition of in vitro and in vivo

Sharifah Sakinah Syed Alwi

Principal Investigator

2014

FRGS

150,000

40.

Investigation of the possible involvement of the serotonergic pathway in zerumbone -induced antinociception in an animal model of neuropathic pain

Enoch Kumar Perimal

Principal Investigator

2015

GP-IPS

15,000

41.

Neuroprotective effect of long-term zerumbone administration on the sciatic nerve morphology in chronic constriction injury mouse model of neuropathic pain

Enoch Kumar Perimal

Principal Investigator

2015

GP-IPS

15,000

42.

Immunopharmacology  of  the  standardized  extracts  of Phyllanthus  amarus and  its  bioactive  compounds  in asthma-related  junctional  complex  disruption, mast cell degranulation  and  lung  remodeling

Daud Ahmad bin Israf Ali

Principal Investigator

2015

NRGS

398,400

43.

Attenuation of proinflammatory endothelial dysfunction with Clinacanthus nutans

Daud Ahmad bin Israf Ali

Principal Investigator

2015

NRGS

426,000

44.

Thymoquinone -LoadedNanostructured Liid Carrier As A Potential Drug Candida For Management of Alzheimer 's Disease And Other Neurodegenerative Disorders

Latifah Saiful Yazan

Principal Investigator

2015

SCIENCEFUND

296,250

45.

Investigation od The Mechanisms of Action Zerumbone -Induced Antiallodynic and Antihyperalgesic effects in Animal Model of Neuropathic Pain

Enoch Kumar a/l Perimal

Principal Investigator

2015

SCIENCEFUND

238,200

46.

Targeting JAK-STAT signaling pathway to revert neurogenic-to-gliogenic

Michael Ling King Hwa

 

Principal Investigator

2015

SCIENCEFUND

 

293,523

 

47.

In Vivo Investigation of The Peripheral Antinociceptive Activity of Diarylpentanoids Analogue

Mohd Roslan Bin Sulaiman

Principal Investigator

2015

FRGS

111,000

48.

Evaluation of the effects of Centella asiatica on atherogenic animal model in vivo, and its active constituents, Asiaticoside and Asiatic Acid, on pre-lesional atherogenesis in Human Aortic Endothelial Cells (HAEC) in-vitro

Zuraini Ahmad

Principal Investigator

2015

FRGS

141,000

49.

The Aphrodisiac and Reproductive Effects of Melicope Ptelefolia (Setenggek Burung) in male rats

Tengku Azam Shah Tengku Mohamad

Principal Investigator

2015

FRGS

139,800